Dimethylformamide → HCID 74949036, compound
Reaction equation
C1(C)C=CC=CC=1.[C:8]([OH:19])(=O)[CH:9]=[CH:10][CH2:11][CH2:12][CH:13]=[CH:14][CH:15]=[CH:16][CH3:17].CN(C=O)C.S(Cl)([Cl:27])=O>C1(C)C=CC=CC=1>[C:8]([Cl:27])(=[O:19])[CH:9]=[CH:10][CH2:11][CH2:12][CH:13]=[CH:14][CH:15]=[CH:16][CH3:17]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 5 °C
Procedure
In an atmosphere of nitrogen, the 2,6,8-decatrienic acid toluene solution obtained in the above and DMF (3.7 g, 0.05 mol) were added to a 100 ml capacity flask, followed by cooling to 5° C. Thionyl chloride (11.9 g, 0.10 mol) was added dropwise to this and stirring was carried out at 5° C. for 0.5 hour to obtain a toluene solution of 2,6,8-decatrienoic acid chloride.
Workup
- additionwere added to a 100 ml capacity flask
Sources & evidence
- ORD record
- ord-f8baae808ba9401d91ae0cd6a04dd613
- Source dataset
- uspto-grants-2012_07
- Patent number
- US08217192B2
Reaction notes
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