反应详情

A solution of {5-({[4-(methyloxy)phenyl]methyl}oxy)-4-[(phenylmethyl)oxy]-2-pyridinyl}methyl acetate (26.3 g, 67 mmol) in dichloromethane (700 ml) was treated with triethylsilane (10 ml, 62.6 mmol)and trifluoroacetic acid (35 ml). After 16 hours the mixture was evaporated and triturated with toluene/ethyl acetate (250 ml/5 ml) affording a white solid that was isolated by filtration and dried in vacuo (22.5 g).

1. customAfter 16 hours the mixture was evaporated
2. customtriturated with toluene/ethyl acetate (250 ml/5 ml)
3. customaffording a white solid
4. customthat was isolated by filtration
5. customdried in vacuo (22.5 g)