Ammonia → 1-Chloro-3-methoxy-5-nitrobenzene

HRID 1517946노트

반응식

HRID 1517946 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([OH:11])[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1.[C:12](=O)([O-])[O-].[K+].[K+].COS(OC)(=O)=O.N>C(O)C.O>[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[C:4]([O:11][CH3:12])[CH:3]=1

참가 물질

7

반응물 4

HCID 222AmmoniaHCID 6497Dimethyl SulfateHCID 11430Potassium CarbonateHCID 106758153-Chloro-5-nitrophenol

생성물 1

HCID 140260501-Chloro-3-methoxy-5-nitrobenzene

시약·촉매·용매 2

HCID 702Ethanol용매2회HCID 962Water용매

실험 절차

10 g 3-chloro-5-nitrophenol are dissolved in 250 ml of ethanol. 11.9 g potassium carbonate and 6 ml dimethylsulphate are added and the mixture is stirred for 12 hours at ambient temperature. Then 3 ml of a 33% ammonia solution are added and then the ethanol is eliminated in vacuo. The residue is taken up in water and the precipitated solid is suction filtered and dried.

후처리

  1. filtrationfiltered
  2. customdried

출처 및 근거

ORD 기록
ord-33e31a16b14943b5bb5a4413f4a8bae3
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08232312B2

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