反应详情

To a solution of the title compound from Example 71 Step B (100 mg, 0.390 mmol) in tetrahydrofuran (2.0 mL) was added aqueous 1 N sodium hydroxide solution (0.390 ml, 0.390 mmol). After stirring for several hours at room temperature, the reaction was concentrated under reduced pressure to provide the title compound: LCMS m/z 241.95 [M+H]+; 1H NMR (500 MHz, CDCl3) δ 8.58 (s, 1H), 8.53 (s, 1H), 7.86 (s, 1H), 1.76-1.74 (m, 2H), 1.29-1.27 (m, 2H).

1. concentrationthe reaction was concentrated under reduced pressure