Dichloromethane → N-{3-[8-(2,6-difluorophenyl)-2-(methylthio)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methylphenyl}-2-thiophenecarboxamide
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:48][N:49]([c:50]1[cH:51][cH:52][n:53][cH:54][cH:55]1)[CH3:56].[Cl:45][CH2:46][Cl:47].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH3:29])[c:6](-[c:8]2[c:9]3[c:10]([n:11][c:12]([S:14][CH3:15])[n:13]2)[n:16](-[c:21]2[c:22]([F:28])[cH:23][cH:24][cH:25][c:26]2[F:27])[c:17](=[O:20])[cH:18][cH:19]3)[cH:7]1.[s:37]1[c:38]([C:42](=[O:43])[Cl:44])[cH:39][cH:40][cH:41]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH3:29])[c:6](-[c:8]2[c:9]3[c:10]([n:11][c:12]([S:14][CH3:15])[n:13]2)[n:16](-[c:21]2[c:22]([F:28])[cH:23][cH:24][cH:25][c:26]2[F:27])[c:17](=[O:20])[cH:18][cH:19]3)[cH:7]1)[C:42]([c:38]1[s:37][cH:41][cH:40][cH:39]1)=[O:43]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d159b2c9817f4ea6b542343273d83450
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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