Tetrahydrofuran → HCID 178431742, compound

HRID 152711Notes

Reaction equation

HRID 152711 reaction equation
[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[Cl:10][c:11]1[n:12][c:13]([NH:18][c:19]2[cH:20][c:21]([CH:24]3[CH2:25][CH2:26]3)[n:22][nH:23]2)[n:14][c:15]([Cl:17])[n:16]1.[F:27][c:28]1[cH:29][cH:30][c:31]([NH:34][C:35](=[O:36])[C:37]2([CH3:42])[NH:38][CH2:39][CH2:40][CH2:41]2)[cH:32][n:33]1>>[c:11]1([N:38]2[C:37]([C:35]([NH:34][c:31]3[cH:30][cH:29][c:28]([F:27])[n:33][cH:32]3)=[O:36])([CH3:42])[CH2:41][CH2:40][CH2:39]2)[n:12][c:13]([NH:18][c:19]2[cH:20][c:21]([CH:24]3[CH2:25][CH2:26]3)[n:22][nH:23]2)[n:14][c:15]([Cl:17])[n:16]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 68472156N-(6-fluoro-3-pyridinyl)-2-methylpyrrolidine-2-carboxamideHCID 178478357HCID 178478357, compound

Product 1

HCID 178431742HCID 178431742, compound

Sources & evidence

ORD record
ord-e00ee19cf0f6489a905a13b7ccc08a00
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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