Sodium Azide → HCID 86673637, compound

HRID 1528781Notes

Reaction equation

HRID 1528781 reaction equation
Br[CH2:2][C:3]1[C:4]([CH3:15])=[N:5][O:6][C:7]=1[C:8]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][CH:9]=1.[N-:16]=[N+:17]=[N-:18].[Na+]>CN(C=O)C>[N:16]([CH2:2][C:3]1[C:4]([CH3:15])=[N:5][O:6][C:7]=1[C:8]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][CH:9]=1)=[N+:17]=[N-:18]

Participants

4

Reactant 2

HCID 33557Sodium AzideHCID 665772234-Bromomethyl-5-(4-bromo-phenyl)-3-methyl-isoxazole

Product 1

HCID 86673637HCID 86673637, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
80 °C

Procedure

To 4-bromomethyl-5-(4-bromo-phenyl)-3-methyl-isoxazole (3.68 g, 11.12 mmol) in DMF (30 mL) was added sodium azide (1.83 g, 27.79 mmol) and the reaction was stirred at 80° C. for 1 hour. After aqueous workup, the mixture was concentrated to give the title compound.

Workup

  1. concentrationAfter aqueous workup, the mixture was concentrated

Sources & evidence

ORD record
ord-4e98d64a7f76473a9905c714a6ee1f98
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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