Tetrahydrofuran → 1-(tert-Butoxycarbonyl)-2'-benzyl-5',6'-dihydrospiro[piperidine-4,4'-[4H]pyrrolo[1,2-b]pyrazole]
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][c:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[n:17][nH:18]2)([CH2:26][CH2:27][OH:28])[CH2:12][CH2:13]1.[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[O:48]=[C:49]([O:50][CH2:51][CH3:52])[N:53]=[N:54][C:55]([O:56][CH2:57][CH3:58])=[O:59].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][CH2:13]1)[c:14]1[cH:15][c:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[n:17][n:18]1[CH2:27][CH2:26]2Participants
5
Sources & evidence
- ORD record
- ord-6ede0fe6817240f9a6119be86ba7509b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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