反应详情

The procedure of Example 1 was repeated except the following. The same reactor as used in Example 1 was charged with 25.0 g (0.124 mole) of a γ-(4-pyridyl)butyric acid hydrochloride with a purity of at least 99%, 25.0 g of water and 1.25 g of 5% Rh/C [0.25% by weight in terms of Rh based on the γ-(4-pyridyl)butyric acid hydrochloride]. The reaction was conducted for 3 hours. A γ-(4-piperidyl)butyric acid hydrochloride was produced in a yield of 98%.