反应详情

温度

23.5 °C

3,5-Dichloro-4-(methylsulfonyl)benzaldehyde (1.5 g), 2-propanol (20 mL), 2,4-pentanedione (1.6 mL), formic acid (44 mL) and piperidine (114 mL) were mixed and stirred at 22-25° C. for 63 h. The product was filtered, washed with 2-propanol and dried (yield 1.0 g, melting point 134-136° C.). 1H-NMR(400 MHz, DMSO-d6 d=2.29 (s, 3H), 2.46 (s, 3H), 3.48 (s, 3H), 7.67 (s, 2 H), 7.71 (s, 1H).

1. filtrationThe product was filtered
2. washwashed with 2-propanol
3. customdried (yield 1.0 g, melting point 134-136° C.)