HCID 9801871, compound → HCID 9824989, compound

HRID 1532643Notes

Reaction equation

HRID 1532643 reaction equation
[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]([CH3:37])[CH2:10][CH2:11][CH2:12][N:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N:15]=[C:14]1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]>C(OCC)(=O)C>[ClH:1].[CH3:37][N:9]([CH3:8])[CH2:10][CH2:11][CH2:12][N:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N:15]=[C:14]1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]

Participants

4

Reactant 2

HCID 9801871HCID 9801871, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 9824989HCID 9824989, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.13 ml) was added to a solution containing N,N-dimethyl-3-(2-pentadecyl-1H-benzimidazol-1-yl)-1-propanamine (0.20 g) in ethyl acetate (2 ml). After being stirred for 20 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-hexane, thereby yielding the entitled compound (0.13 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethyl acetate-hexane

Sources & evidence

ORD record
ord-20e82b5fab2649ee80729924cb92e72e
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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