HCID 9846158, compound → HCID 9869673, compound

HRID 1532645Notes

Reaction equation

HRID 1532645 reaction equation
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:25]1[N:29]([CH2:30][CH2:31][CH2:32][N:33]([CH3:35])[CH3:34])[C:28]2[CH:36]=[CH:37][CH:38]=[CH:39][C:27]=2[N:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:25]1[N:29]([CH2:30][CH2:31][CH2:32][N:33]([CH3:34])[CH3:35])[C:28]2[CH:36]=[CH:37][CH:38]=[CH:39][C:27]=2[N:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

4

Reactant 2

HCID 9846158HCID 9846158, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 9869673HCID 9869673, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.19 ml) was added to a solution containing 3-(2-heptadecyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-propanamine (0.33 g) in ethyl acetate (5 ml). After being stirred for 10 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with ethyl acetate, thereby yielding the entitled compound (0.32 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with ethyl acetate

Sources & evidence

ORD record
ord-9200d9f4de064ba08d6153b591ed8acc
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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