HCID 9845444, compound → HCID 9912263, compound

HRID 1532647Notes

Reaction equation

HRID 1532647 reaction equation
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:25]1[N:29]([CH2:30][CH2:31][N:32]([CH3:34])[CH3:33])[C:28]2[CH:35]=[CH:36][CH:37]=[CH:38][C:27]=2[N:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:25]1[N:29]([CH2:30][CH2:31][N:32]([CH3:33])[CH3:34])[C:28]2[CH:35]=[CH:36][CH:37]=[CH:38][C:27]=2[N:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

4

Reactant 2

HCID 9845444HCID 9845444, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 9912263HCID 9912263, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.12 ml) was added to a solution containing 2-(2-heptadecyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-ethanamine (0.200 g) in ethyl acetate (2 ml). After being stirred for 15 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethanol-ethyl acetate, thereby yielding the entitled compound (0.182 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethanol-ethyl acetate

Sources & evidence

ORD record
ord-b1d48c1005e14ca6becc5857f3731768
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

Loading…