2,5-Dichloronitrobenzene → HCID 3096074, compound

HRID 1532654Notes

Reaction equation

HRID 1532654 reaction equation
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH2:6].Cl[C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=1[N+:16]([O-:18])=[O:17]>C(OCC)(=O)C>[Cl:15][C:12]1[CH:13]=[CH:14][C:9]([NH:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:7])[CH3:1])=[C:10]([N+:16]([O-:18])=[O:17])[CH:11]=1

Participants

4

Reactant 2

HCID 69772,5-DichloronitrobenzeneHCID 7993N,N-Dimethyl-1,3-propanediamine

Product 1

HCID 3096074HCID 3096074, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Conditions

Temperature
125 °C

Procedure

N,N-Dimethyl-1,3-propanediamine (2.92 ml) was added to 2,5-dichloronitrobenzene (2.23 g) and stirred for 14 hours at 125° C. The reaction mixture, with ethyl acetate added thereto, was washed with 1N sodium hydroxide aqueous solution, water and saturated brine successively, dried over sodium sulfate anhydride, and concentrated, thereby yielding the entitled compound (2.99 g) as brown oil.

Workup

  1. washwas washed with 1N sodium hydroxide aqueous solution, water and saturated brine successively
  2. dry with materialdried over sodium sulfate anhydride
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-5b98b9e71fb242de992fba7479966b1c
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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