HCID 9890245, compound → HCID 22013784, compound

HRID 1532674Notes

Reaction equation

HRID 1532674 reaction equation
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:25]1[N:29]([CH2:30][CH2:31][CH2:32][N:33]([CH3:35])[CH3:34])[C:28]2[CH:36]=[CH:37][C:38]([CH3:40])=[CH:39][C:27]=2[N:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:25]1[N:29]([CH2:30][CH2:31][CH2:32][N:33]([CH3:34])[CH3:35])[C:28]2[CH:36]=[CH:37][C:38]([CH3:40])=[CH:39][C:27]=2[N:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

4

Reactant 2

HCID 9890245HCID 9890245, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 22013784HCID 22013784, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.28 ml) was added to a solution containing 3-(2-heptadecyl-5-methyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-propanamine (0.34 g) in ethyl acetate (5 ml). After being stirred for 10 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with a mixed solution of ethanol-ethyl acetate, thereby yielding the entitled compound (0.304 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with a mixed solution of ethanol-ethyl acetate

Sources & evidence

ORD record
ord-d49bf499e7f34b81aeabe93bec063a6c
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

Loading…