HCID 22013766, compound → HCID 22013747, compound

HRID 1532680Notes

Reaction equation

HRID 1532680 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])([O-])=O>C(OCC)(=O)C.[C].[Pd]>[CH2:11]([NH:10][C:5]1[C:4]([NH2:1])=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Participants

4

Reactant 1

HCID 22013766HCID 22013766, compound

Product 1

HCID 22013747HCID 22013747, compoundYield 99.1%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 8857Ethyl AcetateSolvent

Procedure

10% of palladium-carbon (1.52 g) was added to a solution containing N-(2-nitrophenyl)-1-octadecanamine (7.600 g) in ethyl acetate (76 ml) and the mixture was stirred for 18 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (6.95 g) as pink solid.

Workup

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-8ebecda9d7ba4cf2a751581e617e7d34
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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