1,2-Dichloroethane → N-(4-{5,7-Dimethyl-4-[(3,4,5-trimethoxyphenyl)amino]imidazo[5,1-f][1,2,4]triazin-2-yl}phenyl)propanamide

HRID 153283Notes

Reaction equation

HRID 153283 reaction equation
[CH2:23]([Cl:24])[CH2:25][Cl:26].[CH3:16][N:17]1[CH2:18][CH2:19][O:20][CH2:21][CH2:22]1.[CH3:1][CH2:2][C:3]([OH:4])=[O:5].[NH2:27][c:28]1[cH:29][cH:30][c:31](-[c:34]2[n:35][n:36]3[c:37]([c:38]([NH:40][c:41]4[cH:42][c:43]([O:51][CH3:52])[c:44]([O:49][CH3:50])[c:45]([O:47][CH3:48])[cH:46]4)[n:39]2)[c:53]([CH3:57])[n:54][c:55]3[CH3:56])[cH:32][cH:33]1.[OH:6][n:7]1[c:8]2[c:9]([cH:10][cH:11][cH:12][cH:13]2)[n:14][n:15]1>>[CH3:1][CH2:2][C:3](=[O:5])[NH:27][c:28]1[cH:29][cH:30][c:31](-[c:34]2[n:35][n:36]3[c:37]([c:38]([NH:40][c:41]4[cH:42][c:43]([O:51][CH3:52])[c:44]([O:49][CH3:50])[c:45]([O:47][CH3:48])[cH:46]4)[n:39]2)[c:53]([CH3:57])[n:54][c:55]3[CH3:56])[cH:32][cH:33]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 1032Propionic AcidHCID 79724-MethylmorpholineHCID 757711-HydroxybenzotriazoleHCID 11742877N-[2-(4-Aminophenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4-yl]-N-(3,4,5-trimethoxyphenyl)amine

Product 1

HCID 10344915N-(4-{5,7-Dimethyl-4-[(3,4,5-trimethoxyphenyl)amino]imidazo[5,1-f][1,2,4]triazin-2-yl}phenyl)propanamide

Sources & evidence

ORD record
ord-fa8470edaae248509577e0997a81c20f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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