反应详情

[2-(Trimethylsilyl)furo[2,3-c]pyridin-5-yl]methyl acetate (1.3 g, 4.9 mmol) was dissolved in ethanol (50 ml) and treated with potassium carbonate (0.82 g, 5.9 mmol) and heated under reflux for 18 hrs. The mixture was evaporated to dryness and the residue partitioned between ethyl acetate and water. The organic layer was dried, filtered and evaporated to yield the title compound (0.66 g).

1. temperatureheated
2. temperatureunder reflux for 18 hrs
3. customThe mixture was evaporated to dryness
4. customthe residue partitioned between ethyl acetate and water
5. customThe organic layer was dried
6. filtrationfiltered
7. customevaporated