Potassium Iodide → HCID 15030081, compound

HRID 1533918Notes

Reaction equation

HRID 1533918 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1.Cl[CH2:15][CH2:16][CH:17]1[O:21][C:20](=[O:22])[N:19]([CH3:23])[CH2:18]1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC.CC(O)C>[CH3:23][N:19]1[CH2:18][CH:17]([CH2:16][CH2:15][N:11]2[CH2:12][CH2:13][N:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[CH:3]=3)[CH2:9][CH2:10]2)[O:21][C:20]1=[O:22]

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 831111-(m-Tolyl)piperazineHCID 146987465-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one

Product 1

HCID 15030081HCID 15030081, compoundYield 65%

Reagents, catalysts & solvents 2

HCID 2631-ButanolSolventHCID 3776IsopropanolSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 3.5 g (0.02 mol) of 1-(3-methylphenyl)piperazine (Emka-Chemie), 3.3 g (0.02 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 6.4 g (0.06 mol) of anhydrous sodium carbonate and 0.4 g potassium iodide in 100 mL of 1-butanol gave 3.9 g (65%) of white solid, mp 72°-74° C. (2-propanol).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-02fdb174883c4bef87d65385bf36076e
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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