1-Butanol → HCID 15030085, compound

HRID 1533921Notes

Reaction equation

HRID 1533921 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.ClCC[CH:18]1[CH2:22][O:21][C:20](=[O:23])[N:19]1[CH3:24].C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+].[CH2:33](O)[CH2:34]CC>CC(O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:33][CH2:34][CH:22]2[O:21][C:20](=[O:23])[N:19]([CH3:24])[CH2:18]2)[CH2:11][CH2:10]1

Participants

7

Reactant 5

HCID 2631-ButanolHCID 13461-(2-Methoxyphenyl)piperazineHCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 86745448HCID 86745448, compound

Product 1

HCID 15030085HCID 15030085, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 2.9 g (0.015 mol) of 1-(2-methoxyphenyl)piperazine (95%, Aldrich), 2.5 g (0.015 mol) of 5-(2-chloroethyl-3-methyl-2-oxazolidinone, 5.3 g (0.05 mol) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 mL of 1-butanol gave 3.0 g (63%) of off-white solid, mp 107°-108.5° C. (2-propanol).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-8356909ddc0c4b6784516a36328200c1
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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