Formamide → Methyl 2-methoxy-2-methylpropanoate

HRID 1534168Notes

Reaction equation

HRID 1534168 reaction equation
[C:1](N)(=[O:5])C(C)=C.[C:7]([O:12][CH3:13])(=[O:11])[C:8]([CH3:10])=[CH2:9].C(N)=O>>[CH3:1][O:5][C:8]([CH3:10])([CH3:9])[C:7]([O:12][CH3:13])=[O:11]

Participants

4

Reactant 3

HCID 713FormamideHCID 6595MethacrylamideHCID 6658Methyl Methacrylate

Product 1

HCID 12566213Methyl 2-methoxy-2-methylpropanoateYield 8%

Procedure

The reaction product was cooled, and analyzed by gas chromatography. This analysis showed that the conversion of methacrylic acid amide was 94%, the selectivity of methyl methacrylate based on methacrylic acid amide was 91%, and the selectivity of formamide was 98%. In addition, 8% of methyl α-methoxyisobutyrate was obtained in a yield of 8%.

Workup

  1. temperatureThe reaction product was cooled

Sources & evidence

ORD record
ord-5b0db9dc2af64b19813f8f548b63ba37
Source dataset
uspto-grants-1992_02
Patent number
US05087737

Reaction notes

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