Dimethylformamide → (1-{2-[5-(6-Bromonaphthalen-2-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

HRID 153430Notes

Reaction equation

HRID 153430 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7](-[c:12]3[cH:13][n:14][c:15]([CH:17]4[NH:18][CH2:19][CH2:20][CH2:21]4)[nH:16]3)[cH:8][c:9]2[cH:10][cH:11]1.[CH3:22][O:23][C:24](=[O:25])[NH:26][CH:27]([C:28](=[O:29])[OH:30])[CH:31]([CH3:32])[CH3:33].[CH3:58][N:59]1[CH2:60][CH2:61][O:62][CH2:63][CH2:64]1.[O:65]=[CH:66][N:67]([CH3:68])[CH3:69].[P-:34]([F:35])([F:36])([F:37])([F:38])([F:39])[F:40].[n:41]1([O:42][C:43]([N:44]([CH3:45])[CH3:46])=[N+:47]([CH3:48])[CH3:49])[c:50]2[n:51][cH:52][cH:53][cH:54][c:55]2[n:56][n:57]1>>[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7](-[c:12]3[cH:13][n:14][c:15]([CH:17]4[N:18]([C:28]([CH:27]([NH:26][C:24]([O:23][CH3:22])=[O:25])[CH:31]([CH3:32])[CH3:33])=[O:29])[CH2:19][CH2:20][CH2:21]4)[nH:16]3)[cH:8][c:9]2[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 138211012-((Methoxycarbonyl)amino)-3-methylbutanoic acidHCID 666207675-(6-Bromo-naphthalen-2-yl)-2-pyrrolidin-2-yl-1H-imidazole

Product 1

HCID 66620357(1-{2-[5-(6-Bromonaphthalen-2-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

Sources & evidence

ORD record
ord-bf8422ab0dc743059a6eb3a58299bfc9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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