Dimethylformamide → 2-{4-[4-(2-tert-Butyl-6-cyclobutyl-pyrimidin-4-yl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
Reaction equation
[Br:21][CH2:22][CH2:23][CH2:24][CH2:25][N:26]1[C:27](=[O:36])[c:28]2[c:29]([cH:32][cH:33][cH:34][cH:35]2)[C:30]1=[O:31].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([CH:17]2[CH2:18][CH2:19][CH2:20]2)[cH:8][c:9]([N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[n:10]1.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:44][N:45]([CH3:46])[CH:47]=[O:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([CH:17]2[CH2:18][CH2:19][CH2:20]2)[cH:8][c:9]([N:11]2[CH2:12][CH2:13][N:14]([CH2:22][CH2:23][CH2:24][CH2:25][N:26]3[C:27](=[O:36])[c:28]4[c:29]([cH:32][cH:33][cH:34][cH:35]4)[C:30]3=[O:31])[CH2:15][CH2:16]2)[n:10]1Participants
5
Sources & evidence
- ORD record
- ord-bb2cabd52fdc49b2914dab44372bbb68
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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