Benzyl Alcohol → 3-Butenoic acid, phenylmethyl ester

HRID 1534693노트

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HRID 1534693 반응식
C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[CH2:20]([OH:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.[C:28](O)(=[O:32])[CH2:29][CH:30]=[CH2:31].N(C(OCC)=O)=NC([O-])=O>CCOCC>[C:28]([O:27][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:32])[CH2:29][CH:30]=[CH2:31]

참가 물질

6

반응물 4

HCID 244Benzyl AlcoholHCID 11776TriphenylphosphineHCID 327433-Butenoic acidHCID 86599450N-ethoxycarbonyliminocarbamate

생성물 1

HCID 110193853-Butenoic acid, phenylmethyl ester

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

138 g (535 mmol) Triphenylphosphine and 84 ml (812 mmol) benzyl alcohol were added dropwise to 46 g (535 mmol) 3-butenoic acid dissolved in 500 ml ether and 87 ml (535 mmol) ethyl azodicarboxylate and the mixture stirred for 7 hours and allowed to stand overnight. After evaporation of the solvent, the residue was purified by column chromotography (silica gel, hexane/ethyl acetate=95:5) and a sample analysed by thin layer chromatography (hexane:ethyl acetate=1:1) (Rf=0.61).

후처리

  1. customAfter evaporation of the solvent
  2. customthe residue was purified by column chromotography (silica gel, hexane/ethyl acetate=95:5)

출처 및 근거

ORD 기록
ord-42c99eb368ba4c468fb189fcb3f73b4f
출처 데이터셋
uspto-grants-1992_02
특허 번호
US05089662

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