Dimethylformamide → 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(6-morpholinopyridin-3-yl)acetamide

HRID 1535134Notes

Reaction equation

HRID 1535134 reaction equation
[CH3:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][C:15](=[O:16])[OH:17])[cH:12][cH:13]2)[cH:7]1.[CH:55]([N:56]([CH2:57][CH3:58])[CH:59]([CH3:60])[CH3:61])([CH3:62])[CH3:63].[O:18]1[CH2:19][CH2:20][N:21]([c:24]2[cH:25][cH:26][c:27]([NH2:30])[cH:28][n:29]2)[CH2:22][CH2:23]1.[O:64]=[CH:65][N:66]([CH3:67])[CH3:68].[P-:31]([F:32])([F:33])([F:34])([F:35])([F:36])[F:37].[n:38]1([O:39][C:40]([N:41]([CH3:42])[CH3:43])=[N+:44]([CH3:45])[CH3:46])[c:47]2[n:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[CH3:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][C:15](=[O:17])[NH:30][c:27]3[cH:26][cH:25][c:24]([N:21]4[CH2:20][CH2:19][O:18][CH2:23][CH2:22]4)[n:29][cH:28]3)[cH:12][cH:13]2)[cH:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 1040596-(Morpholino)pyridin-3-amineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 58447644[4-(2-Methyl-pyridin-4-yl)-phenyl]-acetic acid

Product 1

HCID 584477512-(4-(2-methylpyridin-4-yl)phenyl)-N-(6-morpholinopyridin-3-yl)acetamide

Sources & evidence

ORD record
ord-9fd398cc3a98425883c14a1a28c93e1b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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