Methanol → 3-Bromo-4-(4-trifluoromethyl-benzyl)-4H-thieno[3,2-b]pyrrole-5-carboxylic acid

HRID 1535626Notes

Reaction equation

HRID 1535626 reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:8]([n:9]1[CH2:10][c:11]1[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]1)[c:21]([Br:24])[cH:22][s:23]2.[CH3:27][OH:28].[Li+:26].[OH-:25]>>[O:2]=[C:3]([OH:4])[c:5]1[cH:6][c:7]2[c:8]([n:9]1[CH2:10][c:11]1[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]1)[c:21]([Br:24])[cH:22][s:23]2

Participants

6

Reactant 5

HCID 887MethanolHCID 961HydroxideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 582976733-Bromo-4-(4-trifluoromethyl-benzyl)-4H-thieno[3,2-b]pyrrole-5-carboxylic acid methyl ester

Product 1

HCID 582976983-Bromo-4-(4-trifluoromethyl-benzyl)-4H-thieno[3,2-b]pyrrole-5-carboxylic acid

Sources & evidence

ORD record
ord-c788d8db81c94c739efabec1501f419d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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