Bromide ion → 2-Cyclopropyl-6-hydroxy-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline
Reaction equation
[Br-:16].[CH2:17]([CH3:18])[Mg+:19].[CH3:20][CH2:21][O:22][C:23](=[O:24])[CH3:25].[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[CH3:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[OH:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH:12]=[O:13])[CH2:6][C:5]2([CH3:14])[CH3:15]>>[OH:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH:12]1[CH2:17][CH2:18]1)[CH2:6][C:5]2([CH3:14])[CH3:15]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-48866694a6324fa2a726cc56e7e151b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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