Methanol → 4-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxymethyl]-1-(3-trifluoromethyl-benzyl)-pyrrolidine-2-carboxylic acid
Reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([CH2:35][c:36]2[cH:37][c:38]([C:42]([F:43])([F:44])[F:45])[cH:39][cH:40][cH:41]2)[CH2:7][CH:8]([CH2:10][O:11][c:12]2[cH:13][cH:14][c:15](-[c:18]3[n:19][c:20]4[n:21]([CH2:32][CH2:33][CH3:34])[c:22](=[O:31])[n:23]([CH2:28][CH2:29][CH3:30])[c:24](=[O:27])[c:25]4[nH:26]3)[cH:16][cH:17]2)[CH2:9]1.[CH3:53][OH:54].[Li+:47].[OH-:46].[OH2:55]>>[O:2]=[C:3]([OH:4])[CH:5]1[N:6]([CH2:35][c:36]2[cH:37][c:38]([C:42]([F:43])([F:44])[F:45])[cH:39][cH:40][cH:41]2)[CH2:7][CH:8]([CH2:10][O:11][c:12]2[cH:13][cH:14][c:15](-[c:18]3[n:19][c:20]4[n:21]([CH2:32][CH2:33][CH3:34])[c:22](=[O:31])[n:23]([CH2:28][CH2:29][CH3:30])[c:24](=[O:27])[c:25]4[nH:26]3)[cH:16][cH:17]2)[CH2:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-cff0b9446ee34b28ab09e1333c3a521a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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