Dimethylformamide → 3-Chloro-5-[(1H-indazol-4-ylmethyl)-carbamoyl]-thiophene-2-carboxylic acid methyl ester
Reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:11](=[O:12])[OH:13])[cH:8][c:9]1[Cl:10].[O:66]=[CH:67][N:68]([CH3:69])[CH3:70].[OH:45][n:46]1[c:47]2[c:48]([cH:49][cH:50][cH:51][cH:52]2)[n:53][n:54]1.[P-:21]([F:22])([F:23])([F:24])([F:25])([F:26])[F:27].[n:28]1([O:29][C:30]([N:31]([CH3:32])[CH3:33])=[N+:34]([CH3:35])[CH3:36])[c:37]2[cH:38][cH:39][cH:40][cH:41][c:42]2[n:43][n:44]1.[nH:55]1[n:56][cH:57][c:58]2[c:59]([CH2:64][NH2:65])[cH:60][cH:61][cH:62][c:63]12>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:11](=[O:13])[NH:65][CH2:64][c:59]2[c:58]3[cH:57][n:56][nH:55][c:63]3[cH:62][cH:61][cH:60]2)[cH:8][c:9]1[Cl:10]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5fe59a98eee547799e451221daa02b55
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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