Sodium ion → 2-(4-Aminomethylphenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole

HRID 1536955Notes

Reaction equation

HRID 1536955 reaction equation
[Al+3:28].[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[nH:10][c:11](-[c:21]3[cH:22][cH:23][n:24][cH:25][cH:26]3)[c:12](-[c:14]3[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]3)[n:13]2)[cH:7][cH:8]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:35][CH2:36][O:37][CH2:38][CH3:39].[H-:27].[H-:30].[H-:31].[H-:32].[Li+:29].[Na+:34].[OH-:33]>>[CH2:1]([NH2:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[nH:10][c:11](-[c:21]3[cH:22][cH:23][n:24][cH:25][cH:26]3)[c:12](-[c:14]3[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]3)[n:13]2)[cH:7][cH:8]1

Participants

9

Reactant 8

HCID 923Sodium ionHCID 961HydroxideHCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 154078722-(4-cyanophenyl)4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole

Product 1

HCID 104501822-(4-Aminomethylphenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole

Sources & evidence

ORD record
ord-ba8d556825dc43f9a70e3c8818f6fc2b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…