Bromide ion → tert-butyl 4-cyclopropyl-2-phenyl-2,5-dihydropyrrole-1-carboxylate

HRID 1537519Notes

Reaction equation

HRID 1537519 reaction equation
[Br-:27].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH:28]1([Mg+:31])[CH2:29][CH2:30]1.[Cu:32]([I:33])[I:34].[c:1]1([CH:7]2[N:8]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:9][C:10]([O:12][S:13]([C:14]([F:15])([F:16])[F:17])(=[O:18])=[O:19])=[CH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]2[N:8]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:9][C:10]([CH:28]3[CH2:29][CH2:30]3)=[CH:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 83717Copper iodideHCID 72357168Tert-butyl 2-phenyl-4-(trifluoromethylsulfonyloxy)-2,5-dihydropyrrole-1-carboxylateHCID 178507030HCID 178507030, compound

Product 1

HCID 178451564tert-butyl 4-cyclopropyl-2-phenyl-2,5-dihydropyrrole-1-carboxylate

Sources & evidence

ORD record
ord-c629479cb7d3400fbc3244ae5b4da147
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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