Tetrahydrofuran → 3-(2-Fluoro-4-iodophenyl)-1-(cyclopropylsulfonyl)-4-fluoro-8-methyl-1H-imidazo[4,5-g]quinazolin-2(3H)-one
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:26][Si:27]([N-:28][Si:29]([CH3:30])([CH3:31])[CH3:32])([CH3:33])[CH3:34].[CH:35]1([S:38](=[O:39])(=[O:40])[Cl:41])[CH2:36][CH2:37]1.[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:24])[nH:11][c:12]3[cH:13][c:14]4[c:15]([CH3:23])[n:16][cH:17][n:18][c:19]4[c:20]([F:22])[c:21]23)[cH:4][cH:5][c:6]([I:8])[cH:7]1.[Li+:25]>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:24])[n:11]([S:38]([CH:35]3[CH2:36][CH2:37]3)(=[O:39])=[O:40])[c:12]3[cH:13][c:14]4[c:15]([CH3:23])[n:16][cH:17][n:18][c:19]4[c:20]([F:22])[c:21]23)[cH:4][cH:5][c:6]([I:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0ad13c1f7da343baab303eb9e46170fd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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