HRID1538191

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID8028

Tetrahydrofuran

C4H8O

HCID11439

Succinimide

C4H5NO2

HCID11776

Triphenylphosphine

C18H15P

HCID220568

Diethyl azodicarboxylate

C6H10N2O4

结构：COc1ccccc1N(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(=O)c1ccc(CO)cc1

HCID19689926

未命名化合物

PRODUCTS

生成物

结构：COc1ccccc1N(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(=O)c1ccc(CN2C(=O)CCC2=O)cc1

HCID19689846

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a2d96017530e4a4b8fd94910401a6bdd
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反应 SMILES

[CH2:75]1[O:76][CH2:77][CH2:78][CH2:79]1.[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[CH:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][N:16]([C:17]([c:18]3[cH:19][cH:20][c:21]([CH2:24][OH:25])[cH:22][cH:23]3)=[O:26])[c:27]3[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]3)[CH2:12][CH2:13]2)[cH:35][cH:36]1.[O:37]=[C:38]1[CH2:39][CH2:40][C:41](=[O:42])[NH:43]1.[O:63]=[C:64]([O:65][CH2:66][CH3:67])[N:68]=[N:69][C:70]([O:71][CH2:72][CH3:73])=[O:74].[OH2:80].[c:44]1([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[cH:58][cH:59][cH:60][cH:61][cH:62]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[CH:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][N:16]([C:17]([c:18]3[cH:19][cH:20][c:21]([CH2:24][N:43]4[C:38](=[O:37])[CH2:39][CH2:40][C:41]4=[O:42])[cH:22][cH:23]3)=[O:26])[c:27]3[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]3)[CH2:12][CH2:13]2)[cH:35][cH:36]1