Pyridine → (3RS,4RS,5SR)-3-hydroxy-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-5-trityloxymethyl-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:36])[CH:11]([c:16]2[cH:17][cH:18][c:19]([O:22][CH2:23][CH2:24][CH2:25][O:26][CH2:27][c:28]3[c:29]([O:34][CH3:35])[cH:30][cH:31][cH:32][cH:33]3)[cH:20][cH:21]2)[CH:12]([CH2:14][OH:15])[CH2:13]1.[CH3:63][N:64]([CH3:65])[c:66]1[cH:67][cH:68][n:69][cH:70][cH:71]1.[Cl:72][CH2:73][Cl:74].[c:37]1([C:43]([Cl:44])([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[cH:38][cH:39][cH:40][cH:41][cH:42]1.[cH:57]1[cH:58][cH:59][n:60][cH:61][cH:62]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:36])[CH:11]([c:16]2[cH:17][cH:18][c:19]([O:22][CH2:23][CH2:24][CH2:25][O:26][CH2:27][c:28]3[c:29]([O:34][CH3:35])[cH:30][cH:31][cH:32][cH:33]3)[cH:20][cH:21]2)[CH:12]([CH2:14][O:15][C:43]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4c9261403c1042ab84ee7b163d84d4d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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