1,2-Dichloroethane → N1-(3-Fluoro-4-(2-(1-propyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-fluorophenyl)malonamide
Reaction equation
[CH2:41]([Cl:42])[CH2:43][Cl:44].[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[cH:16][c:17](-[c:19]1[n:20][cH:21][n:22]([CH2:24][CH2:25][CH3:26])[cH:23]1)[s:18]2.[F:27][c:28]1[c:29]([NH:34][C:35]([CH2:36][C:37](=[O:38])[OH:39])=[O:40])[cH:30][cH:31][cH:32][cH:33]1.[O:55]=[CH:56][N:57]([CH3:58])[CH3:59].[OH:45][n:46]1[c:47]2[c:48]([cH:49][cH:50][cH:51][cH:52]2)[n:53][n:54]1>>[F:1][c:2]1[cH:3][c:4]([NH:5][C:37]([CH2:36][C:35]([NH:34][c:29]2[c:28]([F:27])[cH:33][cH:32][cH:31][cH:30]2)=[O:40])=[O:38])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[cH:16][c:17](-[c:19]1[n:20][cH:21][n:22]([CH2:24][CH2:25][CH3:26])[cH:23]1)[s:18]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ca56d2f6ce594eb99a4a847d04e4b202
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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