2-Methylquinoline → 2-(4-Trimethylsilanyl-but-3-ynyl)-quinoline
Reaction equation
[Br:20][CH2:21][C:22]#[C:23][Si:24]([CH3:25])([CH3:26])[CH3:27].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:13][CH:14]([N-:15][CH:16]([CH3:17])[CH3:18])[CH3:19].[CH3:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1.[Li+:12]>>[CH2:1]([c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1)[CH2:21][C:22]#[C:23][Si:24]([CH3:25])([CH3:26])[CH3:27]Participants
6
Sources & evidence
- ORD record
- ord-47c88bfead7c4e719f214eb80c57924d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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