Dimethylformamide → 3-(2,4-Difluorophenyl)-2-propynoic acid
Reaction equation
[C:10]([C:11]#[CH:12])(=[O:13])[OH:14].[CH:15]([NH:16][CH:17]([CH3:18])[CH3:19])([CH3:20])[CH3:21].[F:1][c:2]1[c:3]([I:9])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[Pd:27]([Cl:28])[Cl:29].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1.[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1>>[F:1][c:2]1[c:3]([C:12]#[C:11][C:10](=[O:13])[OH:14])[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-78f0a5fe37dc4771840b33a72a6388b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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