Tetrahydrofuran → 2-{4-[1-(2-Methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:12][C:11]([CH3:13])([CH3:14])[CH2:10][O:9]2)[cH:6][cH:7]1.[CH3:16][c:17]1[cH:18][cH:19][cH:20][cH:21][c:22]1[CH:23]=[O:24].[Mg:15].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[c:2]1([CH:23]([c:22]2[c:17]([CH3:16])[cH:18][cH:19][cH:20][cH:21]2)[OH:24])[cH:3][cH:4][c:5]([C:8]2=[N:12][C:11]([CH3:13])([CH3:14])[CH2:10][O:9]2)[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-2901046e590f48dcb16fe85ba8b15b8a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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