Tetrahydrofuran → 3-(Azidomethyl)-5-bromopyridine

HRID 1540134Notes

Reaction equation

HRID 1540134 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][OH:9])[cH:5][n:6][cH:7]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[N:27]12[CH2:28][CH2:29][CH2:30][N:31]=[C:32]1[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]2.[c:10]1([P:11]([c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)(=[O:18])[N:24]=[N+:25]=[N-:26])[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[Br:1][c:2]1[cH:3][c:4]([CH2:8][N:24]=[N+:25]=[N-:26])[cH:5][n:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 199401P,P-Diphenylphosphinic azideHCID 2784733(5-Bromo-3-pyridinyl)methanol

Product 1

HCID 576405383-(Azidomethyl)-5-bromopyridine

Sources & evidence

ORD record
ord-118d683142db4d69b852e97afdf0df74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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