Tetrahydrofuran → 3,4,4a,5,6,7,8,8a-octahydro-2H-quinolin-1-yl-[5-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]thiophen-3-yl]methanone
Reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[F:33][C:34]([CH2:35][O:36][S:37]([C:38]([F:39])([F:40])[F:41])(=[O:42])=[O:43])([F:44])[F:45].[N:1]1([C:11](=[O:12])[c:13]2[cH:14][s:15][c:16]([CH:18]3[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]3)[cH:17]2)[CH2:2][CH2:3][CH2:4][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH:10]12>>[N:1]1([C:11](=[O:12])[c:13]2[cH:14][s:15][c:16]([CH:18]3[CH2:19][CH2:20][N:21]([CH2:35][C:34]([F:33])([F:44])[F:45])[CH2:22][CH2:23]3)[cH:17]2)[CH2:2][CH2:3][CH2:4][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH:10]12Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4936ab93dfb74976b081d566cb49e28b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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