Potassium Cation → 5-Chloro-2-(trifluoromethyl)pyridine

HRID 1540319Notes

Reaction equation

HRID 1540319 reaction equation
[CH3:19][N:20]1[CH2:21][CH2:22][CH2:23][C:24]1=[O:25].[CH3:3][Si:4]([C:5]([F:6])([F:7])[F:8])([CH3:9])[CH3:10].[Cl:11][c:12]1[cH:13][cH:14][c:15]([I:18])[n:16][cH:17]1.[Cu:26][I:27].[F-:1].[K+:2]>>[C:5]([F:6])([F:7])([F:8])[c:15]1[cH:14][cH:13][c:12]([Cl:11])[cH:17][n:16]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 13387N-methyl-2-pyrrolidoneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 552549(Trifluoromethyl)trimethylsilaneHCID 111181485-Chloro-2-iodopyridine

Product 1

HCID 135326585-Chloro-2-(trifluoromethyl)pyridine

Sources & evidence

ORD record
ord-a38c0dcc9c924aa292de2c21e904a6a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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