Tetrahydrofuran → N-(3,4-dichlorophenyl)-4-[[1-(2-thiophen-2-ylacetyl)piperidin-3-yl]methyl]piperazine-1-carboxamide
Reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:1][c:2]1[cH:3][c:4]([NH:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][N:15]([CH2:18][CH:19]3[CH2:20][NH:21][CH2:22][CH2:23][CH2:24]3)[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]1[Cl:8].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[s:32]1[c:33]([CH2:37][C:38](=[O:39])[Cl:40])[cH:34][cH:35][cH:36]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][N:15]([CH2:18][CH:19]3[CH2:20][N:21]([C:38]([CH2:37][c:33]4[s:32][cH:36][cH:35][cH:34]4)=[O:39])[CH2:22][CH2:23][CH2:24]3)[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
5
Sources & evidence
- ORD record
- ord-00f4861e468d471f8ba1245480cce208
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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