Acetonitrile → 3-(4-Methylpiperazin-1-yl)carbonyloxy-5-chloro-2-(7-chloro-1,8-naphthyridin-2-yl)isoindolin-1-one
Reaction equation
[CH2:43]([Cl:44])[Cl:45].[CH3:33][N:34]1[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]1.[CH3:40][C:41]#[N:42].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][c:8]([N:12]3[C:13](=[O:32])[c:14]4[cH:15][cH:16][c:17]([Cl:31])[cH:18][c:19]4[CH:20]3[O:21][C:22]([O:24][c:23]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)=[O:30])[n:9][c:10]2[n:11]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][c:8]([N:12]3[C:13](=[O:32])[c:14]4[cH:15][cH:16][c:17]([Cl:31])[cH:18][c:19]4[CH:20]3[O:21][C:22](=[O:24])[N:37]3[CH2:36][CH2:35][N:34]([CH3:33])[CH2:39][CH2:38]3)[n:9][c:10]2[n:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cc67977d26d44457a34c4270e67ff7f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…