1,2-Dichloroethane → 2-tert-butoxycarbonylamino-3-methyl-butyric acid 2-(tert-butyl-diphenyl-silanyloxy-methyl)-5-[4-(dimethylamino-methyleneamino)-2-oxo-2H-pyrimidin-1-yl]-4-hydroxy-4-methyl-tetrahydro-furan-3-yl ester

HRID 1541002Notes

Reaction equation

HRID 1541002 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[SiH2:5][O:6][C:7]([CH:8]1[CH:9]([OH:27])[C:10]([CH3:25])([OH:26])[CH:11]([n:13]2[c:14](=[O:24])[n:15][c:16]([N:19]=[CH:20][N:21]([CH3:22])[CH3:23])[cH:17][cH:18]2)[O:12]1)([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[C:40](=[O:41])([O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[NH:47][CH:48]([CH:49]([CH3:50])[CH3:51])[C:52](=[O:53])[OH:54].[CH2:55]([Cl:56])[CH2:57][Cl:58].[CH3:59][N:60]([c:61]1[cH:62][cH:63][n:64][cH:65][cH:66]1)[CH3:67].[Cl:68][CH2:69][Cl:70]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[SiH2:5][O:6][C:7]([CH:8]1[CH:9]([O:27][C:52]([CH:48]([NH:47][C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[CH:49]([CH3:50])[CH3:51])=[O:53])[C:10]([CH3:25])([OH:26])[CH:11]([n:13]2[c:14](=[O:24])[n:15][c:16]([N:19]=[CH:20][N:21]([CH3:22])[CH3:23])[cH:17][cH:18]2)[O:12]1)([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 270655Boc-DL-valineHCID 131727192N'-{1-[5-(tert-butyl-diphenyl-silanyloxy-methyl)-3,4-dihydroxy-3-methyl-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-N,N-dimethyl-formamidine

Product 1

HCID 1317271912-tert-butoxycarbonylamino-3-methyl-butyric acid 2-(tert-butyl-diphenyl-silanyloxy-methyl)-5-[4-(dimethylamino-methyleneamino)-2-oxo-2H-pyrimidin-1-yl]-4-hydroxy-4-methyl-tetrahydro-furan-3-yl ester

Sources & evidence

ORD record
ord-568bff95c592473d970c706fac087029
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…