Tetrahydrofuran → [2-methyl-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimidazol-4-yl]methanol
Reaction equation
[Al+3:34].[CH3:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH2:7][c:8]1[c:9]([CH3:18])[c:10]([C:14]([F:15])([F:16])[F:17])[cH:11][cH:12][cH:13]1)[cH:19][c:20]([N:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1)[cH:21][c:22]2[C:23](=[O:24])[O:25][CH3:26].[H-:33].[H-:36].[H-:37].[H-:38].[Li+:35].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH3:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH2:7][c:8]1[c:9]([CH3:18])[c:10]([C:14]([F:15])([F:16])[F:17])[cH:11][cH:12][cH:13]1)[cH:19][c:20]([N:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1)[cH:21][c:22]2[CH2:23][OH:24]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-542e18c01c1c48659d686c6cb7aea6c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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