Dimethylformamide → 6-[(2-{[6-(2,4-Dichlorophenyl)-5-nitropyrazin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile

HRID 1541264Notes

Reaction equation

HRID 1541264 reaction equation
[CH:31]([N:32]([CH:33]([CH3:34])[CH3:35])[CH2:36][CH3:37])([CH3:38])[CH3:39].[Cl:1][c:2]1[c:3](-[c:9]2[c:10]([N+:16](=[O:17])[O-:18])[n:11][cH:12][c:13]([Br:15])[n:14]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[NH2:19][CH2:20][CH2:21][NH:22][c:23]1[cH:24][cH:25][c:26]([C:29]#[N:30])[cH:27][n:28]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[Cl:1][c:2]1[c:3](-[c:9]2[c:10]([N+:16](=[O:17])[O-:18])[n:11][cH:12][c:13]([NH:19][CH2:20][CH2:21][NH:22][c:23]3[cH:24][cH:25][c:26]([C:29]#[N:30])[cH:27][n:28]3)[n:14]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 113694056-[(2-Aminoethyl)amino]pyridine-3-carbonitrileHCID 223185103-(2,4-Dichlorophenyl)-5-bromo-2-nitropyrazine

Product 1

HCID 102029556-[(2-{[6-(2,4-Dichlorophenyl)-5-nitropyrazin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile

Sources & evidence

ORD record
ord-211954deaab049e2aaf065e7def1cd8a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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