Hydrochloric Acid → 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-morpholin-4-yl-ethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Reaction equation
[C:46](=[O:47])([OH:48])[O-:49].[CH3:51][N:52]1[CH2:53][CH2:54][CH2:55][C:56]1=[O:57].[Cl:37][CH2:38][CH2:39][N:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1.[ClH:36].[F:3][C:4]([c:5]1[cH:6][c:7]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][C:13]3([C:14](=[O:24])[NH:15][CH2:16][N:17]3[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:25][CH2:26]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35].[H-:1].[Na+:2].[Na+:50]>>[F:3][C:4]([c:5]1[cH:6][c:7]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][C:13]3([C:14](=[O:24])[N:15]([CH2:38][CH2:39][N:40]4[CH2:41][CH2:42][O:43][CH2:44][CH2:45]4)[CH2:16][N:17]3[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:25][CH2:26]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-70b00a23ba594919856b92dd633b9a31
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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