Dimethyl Sulfoxide → (4-Azidomethyl-4-fluoro-piperidin-1-yl)-(3-chloro-4-fluoro-phenyl)methanone

HRID 1542101Notizen

Reaktionsgleichung

[CH2:37]([N+:38]([CH2:39][CH2:40][CH2:41][CH3:42])([CH2:43][CH2:44][CH2:45][CH3:46])[CH2:47][CH2:48][CH2:49][CH3:50])[CH2:51][CH2:52][CH3:53].[CH3:55][S:56](=[O:57])[CH3:58].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[N:7]2[CH2:8][CH2:9][C:10]([F:13])([CH2:14][O:15][S:16]([c:17]3[cH:18][cH:19][c:20]([CH3:21])[cH:22][cH:23]3)(=[O:24])=[O:25])[CH2:11][CH2:12]2)[cH:26][cH:27][c:28]1[F:29].[N-:31]=[N+:32]=[N-:33].[N-:34]=[N+:35]=[N-:36].[Na+:30].[OH2:54]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[N:7]2[CH2:8][CH2:9][C:10]([F:13])([CH2:14][N:31]=[N+:32]=[N-:33])[CH2:11][CH2:12]2)[cH:26][cH:27][c:28]1[F:29]

Komponenten

Edukt 6

HCID 679Dimethyl Sulfoxide

HCID 923Sodium ion

HCID 962Water

HCID 16028Tetrabutylammonium

HCID 33558Azide2×

HCID 10718129toluene-4-sulfonic acid 1-(3-chloro-4-fluorobenzoyl)-4-fluoropiperidin-4-yl-methyl Ester

Produkt 1

HCID 19361720(4-Azidomethyl-4-fluoro-piperidin-1-yl)-(3-chloro-4-fluoro-phenyl)methanone

Quellen und Nachweise

ORD-Eintrag: ord-2b33e6e2184a4193b9395789a7e394c6
Quelldatensatz: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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