Potassium Cation → 2-Chloro-5-(1-ethoxyvinyl)pyrimidine

HRID 1542139Notes

Reaction equation

HRID 1542139 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH2:9]([Sn:10]([CH2:11][CH2:12][CH2:13][CH3:19])([C:14](=[CH2:15])[O:16][CH2:17][CH3:18])[CH2:20][CH2:21][CH2:22][CH3:23])[CH2:24][CH2:25][CH3:26].[F-:27].[K+:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[Pd:34]([Cl:35])[Cl:36].[c:37]1([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1.[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1>>[c:2]1([C:14](=[CH2:15])[O:16][CH2:17][CH3:18])[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 6228DimethylformamideHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 28179Fluoride IonHCID 6066655-Bromo-2-chloropyrimidineHCID 619414Stannane, tributyl(1-ethoxyethenyl)-

Product 1

HCID 143210022-Chloro-5-(1-ethoxyvinyl)pyrimidine

Sources & evidence

ORD record
ord-c59ef33eb07b4243aa59cb4bc338fd60
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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