Dimethyl Sulfide → 5-Bromo-1-(1-hydroxypropan-2-yl)pyridin-2(1H)-one

HRID 154233Notes

Reaction equation

[BH3:17].[Br:1][c:2]1[cH:3][cH:4][c:5](=[O:13])[n:6]([CH:8]([C:9](=[O:10])[OH:11])[CH3:12])[cH:7]1.[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1.[CH3:14][S:15][CH3:16]>>[Br:1][c:2]1[cH:3][cH:4][c:5](=[O:13])[n:6]([CH:8]([CH2:9][OH:10])[CH3:12])[cH:7]1

Participants

Reactant 4

HCID 1068Dimethyl Sulfide

HCID 6331Borane

HCID 8028Tetrahydrofuran

HCID 580705082-(5-Bromo-2-oxopyridin-1(2H)-yl)propanoic acid

Product 1

HCID 580703425-Bromo-1-(1-hydroxypropan-2-yl)pyridin-2(1H)-one

Sources & evidence

ORD record: ord-e202a0cb6f4c42c787f5ccea7bff750b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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